The spread of antimicrobial resistance (AMR) is a major global concern, and the islands of the Southwest Indian Ocean (SWIO) are not exempt from this phenomenon.As strategic crossroads between Southern Africa and the Indian subcontinent, these islands are constantly threatened by the importation of multidrug-resistant bacteria from these regions.In
Lifting and lowering a load on the ocean can be a dangerous task but can be REFRESH made easy and safe by adopting heave compensation (HC) devices.The design and full-scale experimental results of a 3000-m semi-active heave compensation (AHC) system for a 200-T winch are presented in this paper.First, the design requirements are given and the semi-
Objective: Resistance to immune checkpoint inhibitors (ICIs) has been a massive obstacle to ICI treatment in metastatic urothelial carcinoma (MUC).Recently, increasing evidence indicates the clinical importance of the association between hypoxia and immune status in tumor patients.Therefore, it is necessary to investigate the relationship between h
Fluorescence-based DNA readouts are increasingly important in biological research, owing to enhanced analytical sensitivity and multiplexing capability.In this study, we characterize an in-gel polymerase elongation process to understand the reaction kinetics and transport limitations, and we evaluate DNA sequence design to develop signal amplificat
Distributed electricity generation technologies, like solar photovoltaic (PV), have achieved rapid development in recent years, but are constrained by some problems such as low marketization and lag in public services.The peer-to-peer (P2P) electricity trading, which allows direct electricity transactions between local consumers and prosumers, has